Research Scientist (siRNA) Job at JMD Technologies Inc., Lexington, MA

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  • JMD Technologies Inc.
  • Lexington, MA

Job Description

Title: Research Scientist II

Contract Length: 6 months; on-site position

Location: Lexington, MA

Job Summary:

The Research Scientist is a lab-based role with hands on formulation, biophysical and analytical characterization expertise of oligonucleotides for injectable delivery.

Responsibilities:

  • Identifies gaps in technological capabilities provides recommendations to guide the research agenda
  • Manage multiple external collaborations for deliverables
  • Optimize long-term storage and stability conditions of RNAi conjugates and oligonucleotide formulations in general
  • Develop robust analytical methods and assays for QC and developability assessments

Requirements:

  • 3 years of relevant experience with a PHD (LEVEL II) or 3+ years of relevant experience with a Masters (LEVEL I)
  • Subject matter expertise in Pharmaceutical Sciences, oligonucleotide/peptide/antibody characterization, or related scientific disciplines
  • In-depth and hands-on experience in a range of synthesis, characterization, and purification techniques, including but not limited to NMR, HPLC (analytical and preparative), Mass Spectrometry, IR, silica gel and reverse phase chromatography, TLC, recrystallization etc.
  • Acting as formulation subject matter expert for nucleic acid therapeutics.
  • Ability to establish screening assays for oligonucleotides in early discovery.
  • Experience with analytical method development for solubility, viscosity, degradation and rheological assessment for complex oligonucleotides

Job Tags

Contract work,

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